New Study Finds Statin Alternative Reduces Heart Disease Deaths by 25%

Statin Alternative Significantly Reduces Heart Disease Deaths, New Study Finds


Heart disease is a leading cause of death worldwide, with statins being the most commonly prescribed medication for reducing the risk of major cardiovascular events. However, some people cannot tolerate statins due to side effects, while others choose not to take them. A new study has found that bempodoic acid, a daily pill, has the potential to lower the risk of heart attack or stroke for people who cannot or will not take statins.

What is Bempodoic Acid?

Bempodoic acid is a new drug that works by inhibiting an enzyme called ATP citrate lyase, which is involved in the production of cholesterol in the liver. It has been shown to significantly reduce LDL cholesterol levels, which is the \”bad\” cholesterol that can cause plaque buildup in the arteries.

The Study

The study, published in the New England Journal of Medicine, involved over 2,200 patients with a history of heart disease or a high risk of developing it. Participants were randomly assigned to receive either bempodoic acid or a placebo for an average of 14.9 months.

The results showed that bempodoic acid reduced the risk of major cardiovascular events by 25% compared to the placebo group. This included a 30% reduction in the risk of heart attack, stroke, or death from cardiovascular causes.

Side Effects

Like all medications, bempodoic acid can cause side effects. The most common side effect reported in the study was an increase in uric acid levels, which can lead to gout. However, this was generally mild and manageable with medication.


The study provides promising evidence that bempodoic acid could be a viable alternative to statins for people who cannot or will not take them. However, more research is needed to confirm its long-term safety and effectiveness.

If you are considering taking bempodoic acid or any other medication, it is important to talk to your doctor about the potential risks and benefits. A healthy lifestyle, including regular exercise and a balanced diet, is also important for reducing the risk of heart disease.